Science

Scientists have engineered a monoclonal antibody that can protect mice from a lethal dose of influenza A, a new study shows. The new molecule combines the specificity of a mature flu fighter with the broad binding capacity of a more general immune system defender.

What makes people think an AI system is creative? New research shows that it depends on how much they see of the creative act. The findings have implications for how we research and design creative AI systems, and they also raise fundamental questions about how we perceive creativity in other people.

A recent study marks the first reported instance of generative AI designing synthetic molecules that can successfully control gene expression in healthy mammalian cells. As a proof-of-concept, the authors of the study asked the AI to design synthetic fragments which activate a gene coding for a fluorescent protein in some cells while leaving gene expression patterns unaltered. They created the fragments from scratch and dropped them into mouse blood cells, where the sequence fused with the genome at random locations. The experiments worked exactly as predicted and pave the way for new strategies to give instructions to a cell and guide how they develop and behave with unprecedented accuracy.

Simulations suggest that an extraordinary jump in temperatures seen in 2023 and 2024 could simply be natural variability, rather than a new phase of climate change as some researchers have suggested

Spring is a miserable season for those with seasonal allergies. There are effective drug- and non-drug measures that can control most symptoms effectively.

The post Breathing Easy: Treating Allergic Rhinitis first appeared on Science-Based Medicine.

Esther had seven babies yesterday, and I was there when they left the next (on the ground next to the pond) and plopped into the water. She is a great mom and took them on a tour of the pond before leading them up the ramp to dry out (there was one dead baby by the nest and no unhatched eggs). Everyone is in good shape, and I will explain soon why I couldn’t post on her nesting and incubating. (I do have pictures). In the meantime, for a couple of days I will be busy with what’s below, so do bear with me. I have a lot more photos and movies.

Click the photos to enlarge them.

This was taken moments after the babies entered the water for the first time:

After a tour of the pond, they learned to navigate the ramp and went ashore to dry off. Fortunately, it was sunny and warm yesterday. Today will be colder, so I’m a bit worried, but on Friday the highs move into the 70s and even the 80s.  Today feeding begins in earnest, though Esther has been well nourished throughout and a few babies even ate their tiny pellets.

Mordecai has been a great dad, driving off the drakes that keep going after Esther.  I am also able to chase them away, but like all bachelor males, they are relentless.  The fam:

By the way, we’ve run out of readers’ wildlife photos. I am sad.

Groundwater extraction, plate tectonics and consequences of the last glacial period mean that most of the US's biggest cities are sinking

When huge scientific discoveries are made, you may hear that they are “statistically significant” or pass a threshold called “5 sigma” – but those calculations can be manipulated to make claims seem grander than they are, finds Jacob Aron

The growing use of smart home devices is undermining the privacy and safety of domestic workers. New research reveals how surveillance technologies reinforce a sense of constant monitoring and control by domestic workers' employers, increasing their vulnerability and impacting their mental wellbeing.

Redesigning social media to suit different needs of users could make their time online more focused, according to new research.

Redesigning social media to suit different needs of users could make their time online more focused, according to new research.

The Fermi Paradox presents us with a striking contradiction: despite the high probability of numerous civilizations existing throughout the Universe, we've encountered no evidence or communication from any alien intelligence. A new paper just published calculates that we should have a 99% chance of detecting at least one signal from another civilisation—assuming they survive for several hundred years and could be distributed anywhere across the Milky Way galaxy. This calculation further deepens the mystery of our apparent cosmic solitude.

On May 7th, the Japanese space exploration company ispace announced that its HAKUTO-R RESILIENCE lander entered lunar orbit after completing a 9-minute thruster burn. It's now in a stable lunar orbit, and operators will spend the next month testing and preparing for its landing attempt on June 5. This is the company's second attempt at landing on the Moon, after the first attempt crashed in 2023. It's carrying a micro-rover and several science experiments.

NASA’s Psyche mission is on its way to explore a metal-rich asteroid in the asteroid belt between Mars and Jupiter. All was going well since its launch in October 2023 until nasa announced a decrease in fuel pressure for the propulsion system. It uses a solar electric propulsion system, generating thrust with four electric ion engines that expel xenon ions, giving the spacecraft a gentle nudge in the opposite direction. It has been firing its thrusters continuously since May 2024, but in April 2025, engineers detected the pressure drop. Thankfully they have redundancy built in but are still troubleshooting the issue.

The most massive stars in the Milky Way contain one hundred times more mass than the Sun, even more in some cases. These O-type stars are extremely hot, luminous, and blue, and often die in supernova explosions. Astrophysicists want to know how they get so big, and a simple household chemical might hold the answer.

When ISS astronauts return home, they have a hot ride back to Earth's surface. It's been that way since the beginning of human spaceflight to orbital space and beyond. The incoming vehicle uses friction with Earth's atmosphere to slow down to a safe landing speed. The "hot ride" part comes because that friction builds up high temperatures on the spacecraft's "skin". Without protection, the searing heat of atmospheric re-entry could destroy it. This same heating happens to incoming meteoroids as they whip through Earth's atmosphere.

Using a thermal sensor smaller than a grain of sand, engineers have measured the vibrations, or phonons, within individual molecules.

Cases of dementia doubled worldwide between 1990 and 2021, but more than quadrupled in China during the same period

Deep-sea submersibles have been diving for decades, but records show that we have still only explored a tiny area of the deep seabed, which makes up the majority of Earth's topography

If astronomy has a Holy Grail, it's another habitable world. To find one, NASA is working with partners to develop the Habitable Worlds Observatory (HWO). The HWO would be the first telescope built to detect Earth-like planets around Sun-like stars. China is building the Closeby Habitable Exoplanet Survey (CHES), and new research shows that by working together, HWO and CHES would amplify their results.